Arab Private University for Science and Technology

Pharmacy / Teachers

Doctor Saleh Trefi

Dean of Faculty

Certifications

Ph.D. in Chemistry - Biology and Health (Quality control of drugs) University - TOULOUSE III Paul Sabatier (Sciences), Toulouse \ France 2007.
Master II in Sciences and analytical strategy - University Lyon1, Lyon \ France 2004.
MSBM in (Contrôle de la qualité des produits de santé) and (Pharmacologie) - University Lyon1, Lyon \ France 2003.
Bachelor’s Degree in Pharmacy & Pharmaceutical Chemistry 1999.

Language

Arabic.
English.
French

Courses

ICDL.

Skills

Dean of Faculty of pharmacy at Arab Private University of Science and Technology - 2022 Until Present.
Associate Professor in the Department of Pharmaceutical Chemistry and Quality Control (Aleppo University, Faculty of Pharmacy, Aleppo, Syria) and (Arab Private University of Science and Technology Faculty of Pharmacy, Hama, Syria) 2007 - Present.
Post-graduate student in Master and Ph.D, Teaching assistant, Researcher (Lyon, Toulouse, France) 2002-2007.
Pharmacist (Aleppo, Syria) 1999-2002.

Teaching Modules:

Quality control of drugs.
Pharmaceutical chemistry.
Medicinal chemistry.

Other Information

Indexing Syrian International Researchers The Top 100:

One of the top 100 Syrian international researchers (2015). Report issued by Syrian National Erasmus+ Office in cooperation with Syria Erasmus+ Higher Education Reform Experts (HEREs).
One of the top 10 researchers of Aleppo university (2019). Report issued by ministry of higher education.

International Meetings:

Saleh Trefi, Véronique Gilard, Myriam Malet-Martino, Robert Martino, Alassane Ba : Purity control of ciprofloxacin commercial tablets by ¹⁹F NMR spectroscopy. Second French-Syrian Meeting on Chemistry, TOULOUSE, 9 - 13 juillet 2005.
Saleh Trefi, Véronique Gilard, Myriam Malet-Martino, Robert Martino : Analysis of generic commercial formulations of ciprofloxacin, fluoxetine and fluvoxamine by ¹⁹F-NMR and DOSY NMR. First Conference on Pharmaceutical Sciences, ALEP (SYRIE), 10 - 13 avril 2007.
Saleh Trefi, Véronique Gilard, Myriam Malet-Martino, Robert Martino : Apport de la RMN ¹H DOSY à l'analyse de médicaments. Journée Jeunes Chercheurs SFC , TOULOUSE, 23 avril 2007.
Véronique Gilard, Saleh Trefi, Stéphane Balayssac, Myriam Malet-Martino, Robert Martino: DOSY Nuclear Magnetic Resonance (NMR): A New Analytical Tool for Analysis of Fake Drugs. Pittcon, NEW-ORLEANS (USA), 2-7 mars 2008.
Saleh Trefi, Véronique Gilard, Myriam Malet-Martino, Robert Martino: Analysis of illegally manufactured formulations of tadalafil (Cialis®) by ¹H NMR, 2D DOSY 1H NMR and Raman spectroscopy. second Conference on Pharmaceutical Sciences, ALEP (SYRIE), 6-8 avril 2008.
Saleh Trefi: Quality Control of counterfeit and herbal slimming drugs. Fifth Conference of Pharmaceutical Sciences, ALEP (SYRIE), 15-16 may 2017.
Saleh Trefi: Some pharmaceutical applications of NMR. ACPS, ALEP (SYRIE), 15-16 may 2022.
Saleh Trefi: Some Quantitative pharmaceutical applications of IR. AUST, Hama (SYRIE), 6-6-2023

2009 - present: Supervisor of:

Ph.D project of Mr. Samer Housheh. Title: “Studying prasugrel and clopidogrel oxidation products in different Ph using new analytical methods” finished in 2010. Faculty of Pharmacy, University of Aleppo, Syria.
Master project of Mr. Malek Zidan. Title: “Analysis of Syrian Sildenafil tablets by IR spectroscopy” finished in 2011. Faculty of Pharmacy, University of Aleppo, Syria.
Master project of Ms. Aida Maaz. Title: “Preparation and control of Gatifloxacin nanoparticles, for ocular drug delivery” finished in 2016. Faculty of Pharmacy, University of Aleppo, Syria
Master project of Mr. Ziad Kass Hanna . Title: “Computer aided design of novel heat shock protein 90 hnhibitors New strategy in cancer therapy” finished in 2016. Faculty of Pharmacy, University of Aleppo, Syria
Master project of Mme. Hanan Shasho . Title: “Separation and Assay of Four Antihistamine Drugs Diphenhydramine, Chlorpheniramine, Cyproheptadine and Fexofenadine in Pharmaceutical Forms by a Single HPLC Method” finished in 2018. Faculty of Pharmacy, University of Aleppo, Syria.
Master project of Mme. Nour Nashed. Title: “Spectrophotometric methods for Determination of Cefpodoxime proxetil using sulphonphtalein Acid Dyes” finished in 2018. Faculty of Pharmacy, University of Aleppo, Syria.
Master project of Mme. Suha Alnaeb. Title: “Quality assessment of some povidone iodine pharmaceutical products marketed in Syria” finished in 2019. Faculty of Pharmacy, University of Aleppo, Syria
Master project of Ms. Linda Hammash. Title: “Novel ion-pair HPLC methods for the assessment of sitagliptin and pioglitazone in tablets” finished in 2019. Faculty of Pharmacy, University of Aleppo, Syria.
Master project of Mr. Muhamad Esam Kaf Alghazal. Title: “Determination of dimenhydrinate and chlorpheniramine maleate in pharmaceutical forms by new gas chromatography method” finished in 2019. Faculty of Pharmacy, University of Aleppo, Syria.
Master project of Mr. Elias Sakkal. Title: “Quality control of the active Pharmaceutical ingredients of some Pharmaceutical products prior the termination of their shelf life” finished in 2020. Faculty of Pharmacy, University of Aleppo, Syria.
Master project of Mr. Georgeos Andraws. Title: “Ionisable substances chromatography: A new approach for the determination of Ketoprofen, Etoricoxib, and Diclofenac sodium in pharmaceuticals using ion – pair HPLC” finished in 2020. Faculty of Pharmacy, University of Aleppo, Syria.
Master project of Mr. Ali Alhorani. Title: “Infrared techniques for quality control of sibutramin in pharmaceutical and herbal formulations” finished in 2020. Faculty of Pharmacy, University of Aleppo, Syria.

National Pubications:

Malek Zidan, Saleh Trefi, Ahmad Khalil.Qualitative Analysis of Syrian Sildenafil tablets by NIR-IR. Journal of Aleppo University-Medical Sciences. 77; 2011.
Ziad Kas-Hanna, Saleh Trefi. Computer-Aided Drug Design of Novel Adenine Derived Inhibitors of Heat Shock Protein 90 as New Strategy in Cancer Therapy. Arab Journal of Pharmaceutical Sciences. 5 (22): 2015.
Ziad Kas-Hanna, Saleh Trefi. Computer-Aided Drug Design of Novel Carbazol Derived Inhibitors of Heat Shock Protein 90 as New Method in Cancer Chemotherapy. Journal of AL Baath University-Medical Sciences. 38; 2016.
Khalil Kurdi, Abdullah Kataa, Saleh Trefi, Ahmad Mohie Aldeen Ayoubi. Isolation of some aglycones from Arum Dioscorides. Journal of Aleppo University-Basic Science Series. 113; 2016.
Khalil Kurdi, Abdullah Kataa, Saleh Trefi, Ahmad Mohie Aldeen Ayoubi. Isolation of some coumarins from Arum Dioscorides. Journal of Aleppo University-Basic Science Series. 2016
Yahya Shekh Awad, Saleh Trefi. The design of thiazolidindione analouges as anti hyperglycemic based on modeling. Arab Journal of Pharmaceutical Sciences. 5 (5); 2016.
Saleh Trefi, Ahmad Mohie Aldeen Ayoubi, Khalil Kurdi, Abdullah Kataa. Phytochemical Screening of Arum Dioscorides L. leaves. Syrian journal of agricultural research 5 (3); 2018.
Suha Alnaeb, Saleh Trefi, Youssef Al-ahmad. Quality assessment of some povidone iodine pharmaceutical products marketed in Syria. Journal of Homs University-Medical Sciences 41; 2019.
Raghad Helaliy, Fadi Alrouh, Saleh Trefi, Yaser Bitar. Development of a chromatographic method for determination of eucalyptol in oral liquid forms by GC-FID technique. Journal of Aleppo University-Medical Sciences. 144; 2020.
"Metabolic Disorders in Patients with Recurrent Calcium Oxalate Stones: A Prospective Study at Aleppo University Hospital" Aleppo University Research Journal, Medical Sciences Series, Issue No. 174, 2023