Hepatitis E virus (HEV) usually causes self-limited illness in general population, while the illness ranges from asymptomatic form into severe in pregnant women and causes a high rate of mortality in this population, also it potentially associates with fetal death, as well as complications in the mother (such as hemorrhage and fulminant hepatic failure). This study aims to investigate the sero-positivity of HEV IgG antibodies among pregnant women in Damascus, Syria. Samples were collected randomly from 90 pregnant women, aged 16 to 42 years, at various trimesters of pregnancy, from the University Obstetric Hospital in Damascus, during November and December 2016. Commercial enzyme linked immunesorbent assay (ELISA) kit was used to measure the anti HEV specific IgG in the serum. One pregnant woman was found 1/90 (1.1%) to be sero-positive for HEV IgG antibodies, and she had previous miscarriage, without previous jaundice, and she was in her second trimester. As conclusion, this study showed that 89/90 (98.9%) of pregnant women were sero-negative, and the sero-positivity was the lowest in comparison with other countries.
Journal of Chemical and Pharmaceutical Sciences (JCHPS).
2017.
Seroprevalence of Hepatitis E infection among Pregnant Women in Damascus, Syria
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